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Webinar: Rye Genomic Characteristics and Genome Evolution

Highlights In this two-hour webinar, it’s our great honour to have invited six experts in crop genomics arena. Our speakers will give an in-depth interpretation on two Rye genomic studies, which were just recently published on Nature Genetics : 1. Chromosome-scale genome assembly ... Read More

Seadragon genome analysis provides insights into its phenotype and sex determination locus

GENOME EVOLUTION Genome De novo Assembly|Sex determination The whole sequencing works and partial bioinformatic services were provided by Biomarker Techonologies. Abstract “ The iconic phenotype of seadragons includes leaf-like appendages, a toothless tubular mouth, and male pregna... Read More

Application of Nanopore full-length transcriptome sequencing in isoform-level AS study

TRANSCRIPTOMICS natureCOMMUNICATIONS Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals downregulation of retained introns Full-length transcripts| Nanopore sequencing| Alternative isoform analysis Background Somatic mutations in ... Read More

Latest successful cases on Nanopore RNA-Sequencing with Biomarker Technologies

Nanopore-based Full-length Transcriptome Sequencing Nanopore sequencing distinguishes itself from other sequencing platforms, in that the nucleotides are read directly without DNA synthesis and generates long reads at tens of kilobases. This empowers direct read-out of full-length transcript... Read More

Application of full-length amplicon sequencing in microbial diversity studies

MICROBIAL ECOLOGY Agricultural intensification reduces microbial network complexity and the abundance of keystone taxa in roots Full-length Amplicon Sequencing (ITS) | PacBio HIFI Highlights Agricultural intensification has become increasingly problematic due to its adverse environ... Read More

Investigation of microbiome community and function in immobilized bacteria treated soil by full-length 16S sequencing

MICROBIAL Bacterial compatibility and immobilization with biochar improved tebuconazole degradation, soil microbiome composition and functioning Full-length 16S amplicon sequencing | PacBio HiFi | Alpha diversity | Beta diversity In this study, full-length 16S amplicon sequencing b... Read More

Performance of nanopore long reads in metagenomic studies

METAGENOMICS Complete, closed bacterial genomes from microbiomes using nanopore sequencing Nanopore Sequencing | Metagenomics | MAGs | Bacterial genome circularization | Gut microbiota Highlights 1.A novel method to extract long fragments of DNA was presented in this study, wh... Read More

Application of Nanopore long-read resequencing in the fight against disease

HUMAN GENOMICS nature genetics Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease ONT resequencing | Illumina | Whole exome sequencing | CRISPR-Cas9 ONT targeted sequencing | RNA-seq | ONT 5mC methylation calli... Read More

Application of Nanopore-based re-sequencing in COVID19 genetic variants identification

WHOLE GENOME RESEQUENING Genomics monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response Nanopore | Illumina | Whole genome resequencing | metagenomics | RNA-Seq | Sanger Biomarker Technologies provided technical support on sample seque... Read More

Structure variants in Chinese population and their impact on phenotypes, diseases and population adaptation

WHOLE GENOME RESEQUENCING Structure variants in Chinese population and their impact on phenotypes, diseases and population adaptation Nanopore | PacBio | Whole genome re-sequencing | Structural variation callling In this study, Nanopore PromethION sequencing was provided by Biomark... Read More

Four telomere-to-telomere assembled animal and plant genomes

T2T GENOME ASSEMBLY, GAP FREE GENOME 1st Two Rice Genomes1 Title: Assembly and Validation of Two Gap-free Reference Genomes for Xian/indica Rice Reveals Insights into Plant Centromere Architecture Doi: https://doi.org/10.1101/2020.12.24.424073 Posted Time: January 01, 2021. Institute: ... Read More

Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution

GENOME EVOLUTION nature COMMUNICATIONS Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution PacBio | Illumina | Hi-C | WGS | Genetic Diversity | Demographic History | Gene Flow The Pacbio sequencing, genome de novo assembly an... Read More

A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes

GENOME EVOLUTION nature genetics A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes PacBio | Illumina | Bionano Optical Map | Hi-C Genome Assembly | Genetic Map | Selective Sweeps | RNA-Seq | ISO-seq | SLAF-seq Biomarker Technolo... Read More
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